Detalhe da pesquisa
1.
ABCB1-dependent collateral sensitivity of multidrug-resistant colorectal cancer cells to the survivin inhibitor MX106-4C.
Drug Resist Updat
; 73: 101065, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38367548
2.
Residues forming the gating regions of asymmetric multidrug transporter Pdr5 also play roles in conformational switching and protein folding.
J Biol Chem
; 298(12): 102689, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36370844
3.
How fungal multidrug transporters mediate hyper resistance through DNA amplification and mutation.
Mol Microbiol
; 118(1-2): 3-15, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35611562
4.
An A666G mutation in transmembrane helix 5 of the yeast multidrug transporter Pdr5 increases drug efflux by enhancing cooperativity between transport sites.
Mol Microbiol
; 112(4): 1131-1144, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31294884
5.
Correction: Residues forming the gating regions of asymmetric multidrug transporter Pdr5 also play roles in conformational switching and protein folding.
J Biol Chem
; 299(4): 104666, 2023 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-37044027
6.
Robust, pleiotropic drug resistance 5 (Pdr5)-mediated multidrug resistance is vigorously maintained in Saccharomyces cerevisiae cells during glucose and nitrogen limitation.
FEMS Yeast Res
; 18(4)2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29668941
7.
Advances in the structure, mechanism and targeting of chemoresistance-linked ABC transporters.
Nat Rev Cancer
; 23(11): 762-779, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37714963
8.
Residues from Homologous Transmembrane Helices 4 and 10 Are Critical for P-Glycoprotein (ABCB1)-Mediated Drug Transport.
Cancers (Basel)
; 15(13)2023 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37444569
9.
Nonsynonymous Mutations in Linker-2 of the Pdr5 Multidrug Transporter Identify a New RNA Stability Element.
G3 (Bethesda)
; 10(1): 357-369, 2020 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31757931